Our group is in the department of Chemical and Biomolecular Engineering at the University of California, Berkeley. We are a team of highly interdisciplinary scientists working at the intersection of nanomaterials research, single-molecule studies, and their application to the study of life.
Recent advances in single-molecule techniques have enabled researchers to probe the behavior of living systems at the scale of the biological building blocks of which living systems are comprised. Methods such as single-molecule fluorescence microscopy, optical traps, and molecular dynamics provide a comprehensive set of tools with which to uncover single-molecule biological interactions. These techniques and instruments have allowed us to study molecules at their own size scales, giving us an unprecedented amount of information about the way single biological molecules behave in the absence of ensemble averaging. Similarly, nanotechnology has focused on the study of the unique physical and electronic properties materials acquire when their electrons are confined to the nano-scale. We exploit these unique properties to better visualize biological processes in cells, tissues, and organisms.